02/13/25

Biosemiotics and the Origins of Life on Earth (Part 8 of 8)

0316 Oxygen gas is a byproduct of photosynthesis.  Over billions of years, the continual release of oxygen transforms the atmosphere of the Earth.

The ubiquity of oxygen gas in today’s atmosphere makes experimental research into the chemistry of the early Earthdifficult.  Today, the reaction that Sharov suggests, the oxidation of an alkane to a fatty acid, would require elaborate precautions.  Why?  Even a trace amount of oxygen would directly react with the light-absorbing pigment.

0317  So, what am I saying?

Well, research is difficult.

0318 Also, as soon as one gets to the earliest forms of life on Earth, such as photosynthetic prokaryotes, the “genomic complexity” (nominally, the length of DNA that belongs to only functional genes) is already high.  If one plots the genomic complexity of (1) prokaryotes, such as bacteria, (2) single-celled eukaryotes, such as amoebas, (3) multicellular water animals, such as fish (4) invertebrate land animals, such as worms, and (5) vertebrate land animals, such as mammals, versus time for first fossil evidence, one gets the following graph.

 0319 On one hand, Sharov concludes that the genomic complexity doubles every 340 million years since the start of the Earth.

On the other hand, Sharov points out that, if one projects the line down to zero genomic complexity, the intersection occurs a little over 9 billion years ago.  But, the Earth is only 4.5Byr.

Fortunately, the universe is around 15 billion years old.

0320 If the early Earth is seeded, then biologists already have a label, “panspermia”.

All other planets and moons in the solar system should be similarly seeded.

So, future space exploration may provide an answer.

If it turns out that the early Earth is seeded through panspermia, then research into the origins of life (in general) becomes even more difficult.

0321 Now, I conclude.

Sharov and Tonnessen’s noumenal overlay characterizes biosemiotics.

The Deacon-Tabaczek interscope characterizes emergence.

Both relational structures apply to inquiry into the origin of life on Earth.

This examination demonstrates how the two relational structures relate to one another and constitute complementary approaches for further inquiries into the origins of life.

0322 But, what I have learned concerns more than the topic of the origin of life.

This is significant.

Sharov and Tonnessen’s noumenal overlay may “expand” to include the entire D-T interscope, which includes both the specifying and the exemplar sign-relations.

0322 By extension, the S&T noumenal overlay associates to any three-level interscope, containing two sign-relations,according to the comparison in the following figure.

0323 The topic of the origin of life on Earth turns into a valuable insight into biosemiotics, emergence, and two sign-relations.

02/12/25

Looking at Gustavo Caetano-Anolles’ Chapter (2024) “Evolution of Biomolecular Communication” (Part 1 of 10)

0324 The text before me is chapter ten in Pathways to the Origin and Evolution of Meanings in the Universe (2024, edited by Alexei Sharov and George E. Mikhailovsky, pages 217-243).  The author hails from the Evolutionary Bioinformatics Laboratory at the Department of Crop Sciences and Carl R. Woese Institute for Genomic Biology, at the University of Illinois, Urbana, Illinois, USA.  The author and editors have permission to use and reprint this commentary.

From prior examinations, I propose that Alexei Sharov’s and Morten Tonnessen’s 2021 book, Semiotic Agency, formulates a noumenal overlay for the diverse field of biosemiotics.  All manifestations of semiotic agency are unique.  Each is a subject of inquiry on its own.  Yet, they have one relational structure in common.  Here is a picture of that dyadic actuality.

0325 Biosemiotics is not divorced from science.  Scientists observe and measure phenomena, then build models based on those observations and measurements.  The real elements in the above figure support phenomena.  The contiguities (in brackets) call for models.

0326 So, what about communication mediated by biomolecules?

0327 In the introduction (section 10.1), the author reminds the reader of two premodern views of biological behaviorsand how they change over time.  One is the force of life (in French, le pouvoir de vie), which tends to increase complexity.  The other is the influence of circumstances (in French, l’influence des circonstances), which tends to select for… um… survivors.

These premodern views fit nicely into the contiguities in the above relational structure.  Each dyad can be compared to Aristotle’s hylomorphe of matter [substance] form, allowing the following comparison.

0328 The force of life tends towards the many.

The influence of circumstances tends toward the few.. or rather… one goal.

Surely, my assignments are confusing, because the force of life is singular and circumstances tend to vary.  Also, real initiating events can vary.  But, goals tend to rule out alternatives.

0329 The author then draws upon a recently translated papyrus scroll, attributed to Empedocles.  Empedocles speaks of two opposing forces, one capable of growing things together from the many and one capable of growing things apart.  The former is labeled, “love”, the latter, “strife”.

0330 I wonder, “How does this ancient distinction fit into the schema pictured above?”

Here is my suggestion.

I have a 50:50 chance of being correct.

0331 Strife goes with the force of life, tending towards the many.  Love goes with the influence of circumstances and tends towards a singular goal.

Both are substances and reflect (however distantly) Aristotle’s exemplar: matter [substance] form.

In the above figure, the real initiating event is like an form that conjures matter (information). At the same time, that matter (information) substantiates another form (goal).  This conjured matter (information [love]goal) encompasses the presence that accounts for semiotic agency as a thing.  

0332 What does that imply?

As [strife] acquires information, [love] moves closer to its goal. 

02/11/25

Looking at Gustavo Caetano-Anolles’ Chapter (2024) “Evolution of Biomolecular Communication” (Part 2 of 10)

0333 Well, what if matter… er… information… consists of multiple biomolecules that are… um… modular… in so far as they… because of circumstances… simultaneously engage in a cooperative endeavor… a “love”, so to speak?

Some would say that this what if is similar to the hierarchical relation between parts and a whole.

But, would the whole be the form associated with goal or the form associated with the real initiating event?

Or, would it be the thing called “semiotic agency”?

0334 At the start of section 10.2, the author lays this ambiguous multiple metaphor onto the procrustean bed of an evolutionary paradigm, where (on a molecular level) biological parts are added to one another in a piecemeal way to an evolving system.

The author proposes a phylogenomic-based biphasic model of module creation that explains evolutionary growth in biochemical systems.  In phase one, modules nest within one another, in a provisional sort of way, until over time or suddenly, the form that is goal clarifies. Different modules start to work together as a semiotic agent. In phase two, modules working within that functioning cooperative change as semiotic agency diversifies.

0335 The second phase associates to “adaptation”.

The first phase does not have a proper name.  I suggest the term, “empedoclement”. 

An empedoclement is the inverse of an impediment.

0336 Here is an analogy.

Recently, I joined a tennis club.  I trained to play the game by enduring real initiating events and reviewing information on my performance.  Since I am so modular, different aspects of me perform independently of one another, so I did not adapt well to the circumstances. My instructor says that if I don’t think about what I am doing with each of my modules,then I could move holistically in a coordinated manner.  I will become an adept, rather than a lackluster player full of impediments.

0337 One would think that routinely training and playing tennis would lead to (perhaps slow, but) steady improvement towards the goal of being competitive.  This is a matter of adaptation.  All the facets of mind and body are modular.  Each module develops along its own trajectory. In apparent stasis, improvement is held at bay by one or two recalcitrant modules. In surprisingly fast change, two or more modules improve in tandem.  The fast change could be an empedoclement.

0338 While this analogy helps, I find it difficult to imagine that first phase, where parts are present and may afford some advantages, but no one part realizes the game that is afoot.

0339 The author offers two images as metaphors for the phylogenomic-based biphasic model.

One metaphor is a tree, where the roots represent modules, the trunk stands for the modules coalescing into matter [love] form, where matter is information and the form is a telos or an end.  

The other metaphor portrays modules themselves, which over time, interact to generate scaffolds and active sites, until a robust combination constellates.

Here is a picture of the second metaphor.

0340 The word, “constellates”, is a psychological term (actually, Jungian) that marks the coming into presence (esse_ce) of an archetypal form (essence).  The result may be called “a primordial image”.

For example, the archetype of the king may constellate in a variety of ways, including the duplicitous and the honest, the greedy and the beneficent, as well as the foolish and the wise.  Each pair of these primordial images informs us of a module within the one archetype and how that module can yield different responses to similar circumstances.

0341 But, can the word, “constellate”, also label the coming together of modules within an archetype as an empedoclement?

02/10/25

Looking at Gustavo Caetano-Anolles’ Chapter (2024) “Evolution of Biomolecular Communication” (Part 3 of 10)

0342 How about a hypothetical example?

Cellulose is composed of glucose molecules that are beta-linked to one another.  Starch is composed of glucose molecules that are alpha-linked to one another.  Beta-linked polysaccharides cannot be digested.  Alpha-linked polysaccharides are easy to digest.  

0343 Imagine a bacteria that has a receptor capable of clinging to cellulose, but cannot break the beta-linkage.  It binds because exposed cellulose associates to plant damage and plant damage releases various nutrients, including alpha-linked polysaccharides.  This bacteria is an opportunist.

0344 At this point, I find it hard to predict what happens next.  A biosemiotic reality is going to unfold, but I don’t know how. 

I do know that phenomena of this biosemiotic constellation objectify the following noumenal overlay.  If I want to scientifically study this specific bacteria, then the real elements of the noumenal overlay give rise to phenomena.  Phenomena may be observed and measured.  The observations and measurements may be modeled.  The models account for the contiguities.

0345 Now, this prokaryotic bacteria is not the only living thing that can take advantage of sites of plant damage.  Wood-eating insects do the same.  They chew into wood, not because they can digest the beta-linked cellulose, but because they get… well… the same nutrients that the cellulose-binding bacteria want to feed on.

02/8/25

Looking at Gustavo Caetano-Anolles’ Chapter (2024) “Evolution of Biomolecular Communication” (Part 4 of 10)

0346 Then what happens?

Wood-eating insects, who create the damage that attracts the cellulose-clinging bacteria, inadvertently ingest these bacteria, who do not create the damage that nourishes them.  Bacteria are only present to exploit a long-established relation between exposed cellulose and food.

So, when a cellulose-clinging bacteria gets ingested, it can serve as food for the termite (if it dies) or it can simply pretend that nothing significant has changed (if it lives).  Bacteria can still hold onto cellulose in the termite’s gut and compete for food with the termite’s own digestive system.

0347 The bacteria’s competition with the termite’s own capacity to digest alpha-linked polysaccharides presents a signaling error.  It is as if exposed cellulose (SVs) no longer indicates that food is in the vicinity (SOs) according to the ways that this bacteria interprets the world (SIs).

0348 The specifying sign-relation fails because the bacteria clings to cellulose inside the wood-eating insect’s gut, but this no longer indicates that alpha-linked polysaccharides are available for food.

0349 Then what happens?

Well, phase one ends in this hypothetical scenario when the two independent biomolecular capacities that are innate in the bacteria, the ability to latch onto cellulose and the ability to cleave glucose from alpha-linked polysaccharides, get bound to one another.  Now, a beta-linked polysaccharide chain may be held by the latching molecule and be conformationally distorted enough that a terminal glucose can be cleaved by the original cleaving enzyme.

0350 The bacteria lives off some of the glucose that it liberates.  But, the potential source of glucose has changed from the starchy alpha-linked polysaccharides that both insect gut and bacteria digest to include previously undigestible beta-linked polysaccharides now available to the bacteria.  Indeed, the bacteria release more glucose into the gut than what is available from alpha-linked polysaccharides.

The insect already has pathways for transporting glucose from the gut to the body.

The insect uses the free glucose for its own metabolism.  All it needs to do is eat more wood and keep transporting liberated glucose out of its gut, so there is no build-up of soluble glucose in the gut and the bacteria keep that beta-link cleaving pathway operating.

02/7/25

Looking at Gustavo Caetano-Anolles’ Chapter (2024) “Evolution of Biomolecular Communication” (Part 5 of 10)

0351 In terms of the S&T noumenal overlay, a beta-linked polysaccharide in the claws and jaws of the “holder” and “cleaver” biomolecules is like an emergent being.

0352 Now, natural selection enters the picture.  Bacteria with the innovation prosper.  Bacteria with improvements on the innovation prosper even more.

Plus, the wood-eating insect comes under natural selection as well.

0353 Phase two of diversification follows.

0354 At this point, I must remind myself that this scenario is hypothetical.

It is a fiction that is more than a confection (an elaborate frivolous construction), even though it contains a confection (a compounding of two things).

To some, this confection (sugary delicacy) may taste implausible.

But, it offers the curious flavor of an empedoclement.

02/6/25

Looking at Gustavo Caetano-Anolles’ Chapter (2024) “Evolution of Biomolecular Communication” (Part 6 of 10)

0355 The sign-elements associated to the S&T noumenal overlay conveys the new message.

For the specifying sign, exposed cellulose in the wood-eating insect’s gut2a (SVs) stands for the emergent being of a conformationally-distorted beta-linked polysaccharide held in the jaws of a cleaving enzyme2b (SOs) in regards to bacterial self-governance3b operating on potential courses of action1b (SIs).

For the exemplar sign, the emergent being of a beta-linked polysaccharide bound to “the claws and jaws” of new complex2b (SVe) stands for a seemingly endless source of glucose from ingested cellulose2c (SOe) in regards to what certain bacteria in the insect’s gut3c are capable of doing1c (SIe).

0356 Each of the sign-vehicles and the sign-objects have observable and measurable facets that will eventually go into scientific models.  The scientific models will assist in accounting for each of the sign-interpretants.

Biosemiotic research may be conducted after phase one is complete.

Biosemiotic research can never tell whether phase one is proceeding.

This is the way of empedoclement.

0357 It seems that the wood-chewing insect, so empowered, would go berserk and start to eat every living plant.

Like ripples in still water, biosemiotic waves propagate.

If these wood-chewing insects go after a living plant, then all that plant needs to do is develop a toxin that poisons those little beta-linkage breaking bacteria.  Problem solved.

Okay, so these new insects are not invulnerable?

0358 Tell that to the exterminator.

The exterminator facing a wood-eating insect infiltration, knows that certain principles apply.  He assesses signs.  Is communication (section 10.3) an issue here?  I suppose that depends on who is doing the talking and who is receiving the message.

0359 Peirce’s definition of a sign as a triadic relation is crucial for biosemiotics.  So, are Peirce’s three categories.  Even before getting to a question of communication, there is a character to the S&T overlay that embodies the relational structure of specifying and exemplar sign-relations.

Here is a picture.

0360 These sign-elements, in turn, represent locations in a three-level interscope.  An interscope is a category-based nested form composed of category-based nested forms.  Each nested form exhibits a normal context3, actuality2 and potential1. Then, the nested forms compose the three levels of contenta, situationb and perspectivec.

See A Primer on the Category-Based Nested Form and A Primer on Sensible and Social Construction, by Razie Mah, available at smashwords and other e-book venues.

0361 I will not show a picture of the three-level interscope.

Instead, here is how the elements of the three-level interscope correspond to elements in the S&T noumenal overlay.

0362 For the specifying sign-relation, a content-level actuality2a (SVs) stands for a situation-level actuality2b (SOs) in regards to a situation-level normal context3b and potential1b (SIs).

For the exemplar sign-relation, the situation-level actuality2b (SVe) stands for a perspective-level actuality2c (SOe) in regards to a perspective-level normal context3c and potential1c (SIe).

0363 In terms of communication, I can imagine that the SVs is like a transmission sent and the SOe is like the transmission received.

02/5/25

Looking at Gustavo Caetano-Anolles’ Chapter (2024) “Evolution of Biomolecular Communication” (Part 7 of 10)

0364 According to Shannon’s information theory, which offers a mathematical model for “information” occurring in human-mediated electro-magnetic transmissions, there are five components to the whole process: (i) an information source, (ii) a transmitter, (iii) a channel, (iv) a receiver and (v) a destination that serves as an information sink.

0365 Can I draw associations to the S&T noumenal overlay?

I suppose so.

0366 The specifying sign-interpretant3b,1b (SIs) is like an information source (i) and the specifying sign-vehicle2a (SVs) associates to the transmission (ii) of something2a that stands for information2b (SOs).  Maybe, I can say that the SVs is like a transmitter (ii) and SOs is like that transmission entering the proper channel (iii).

The SOs is contiguous with SVe, so a transmission in the proper channel2b (iii) constitutes an exemplar sign-vehicle2b(SVe) that stands for a perspective-level actuality2c (SOe) (iv), according a perspective-level normal-context3c and potential1c (SIe) (v).  So, the SOmay be labeled as a receiver (iv) and the exemplar sign-interpretant3c,1c (SIe) associates to the information sink or destination (v).

0367 Here is a picture.

0368 Of course, my associations are both evocative and fallible.

Here are three implications (F, G, H).

0369 First (F), Shannon’s theory of communication regards biosemiotic sign-interpretants as sources (i) and receivers(iv).  These are precisely the elements in the S&T noumenal overlay that need to be explained.  Shannon’s theory places them in black boxes and treats them as givens.

What does that imply?

From the point of view of biosemiotics, I wonder, “What is Shannon’s theory actually modeling?”

0370 After all, if I go to the start of the chapter, the two crucial aspects involved in biological change, as characterized by the premoderns, correspond to sign-interpretants.

0371 Shannon’s theory of communication takes these two primordial aspects for granted, in order to concentrate on another question.

What is the channel’s capacity to carry information?

0372 What is so important about the channel2b (iii)?

Hmmm. I see that the channel2b corresponds to “information2b” and to SOs[and]SVe.

What is that about?

Is [and] the same as [contiguity]?

Is this topic about to get fuzzy?

0370 Second (G), Shannon’s theory of communication, as depicted above, is consistent with a biosemiotic approach in regards to the sources of phenomena for communication: transmitter (SVs) (ii), channel (SOs [and] SVe) (iii)  and receiver (SOe) (iv).

Okay, so everything’s fine.

0371 Does that mean that Shannon’s theory of communication somehow is relevant to the hypothetical scenario where the... um… vehicle of a beta-linked polysaccharide2a (SVs) is “transmitted” then “received” as the object of glucose molecules ready to power a wood-eating insect’s metabolism (SOe)?

In this case, does the term, “information2b“, correspond to “the ability of a gut bacteria’s dual-modular claw and jaw apparatus to cleave the terminal glucose of a beta-linked polysaccharide”?

It makes me wonder about the meaning, the presence and the message underlying the word, “information2b“.

There seems be a lot going in within the situation-level actuality2b, which is where the SOs transits into the SVe.

0372 Third (H), Shannon’s theory of communication, expressed as an application of the S&T noumenal overlay,presents a simplification that drags the inquirer to that confounding channel2b.

After all, the channel (iii) goes with phenomena.

In human electronic communication technology, the channel2b can carry only so much information2b.  Noise is the loss of information2b.  Is “noise” information that can no longer be properly received?  Or is “noise” some lacking that makes information no longer salient?

Questions like these, as problematic as they are, seem well-cogitated compared to ones that arise when Shannon’s theory of communication is transferred from the dyadic S&T noumenal overlay to a three-level interscope containing the specifying and exemplar sign-relations.

02/4/25

Looking at Gustavo Caetano-Anolles’ Chapter (2024) “Evolution of Biomolecular Communication” (Part 8 of 10)

0373 Recall the unexpected and twisted path from point 0270 to point 0300?

Now, maybe I should start getting used to that storyline.

0374 Why?

It’s the story of the evocation of thirdness by firstness.

0375 Initially, Sharov and Tonnessen’s noumenal overlay associates to the specifying sign relation.

Once the Deacon and Tabaczek interscope for emergence enters into the picture, the S&T noumenal overlayincorporates the exemplar sign relation.

0376 Initially, Sharov and Tonnessen’s noumenal overlay belongs to what is of the Positivist’s judgment.  It belongs to firstness.  Yet, it touches base with secondness, in so far as its own dyadic structure serves as a guide for discerning what should be regarded as phenomena and what is in need of being modeled.

This makes sense, in so far as biosemiotics is the study of the relational thing that all biological entities have in common.

0377 I mean really, how is a biologist going to examine a sample of the relational thing that all biological entities have in common?

Hey, who left a biosemiotic slide in the microscope?

Is it Shannon?

Let me take a look.

0378 Yeah, it’s Shannon’s alright.  It has information theory written all over it.

But now, the associations are even more evocative.

0379 The two tendencies that the premoderns identified, the force of life and the influence of circumstances, now associate to normal contexts and potentials.  The stuff of strife (situation-level) and love (perspective-level) associate to both thirdness and firstness.  These are the things that biosemiotics is supposed to account for.

0380 Shannon’s information theory fixates on the virtual nested form in the realm of actuality.

0381 The perspective-level actuality2c of a receiver2c virtually brings the situation-level actuality2b of a channel2b into relation with the potential of a content-level information transmitter2a.

Yes, these actualities manifest phenomena that can be observed and measured.  Shannon’s information theory assists in modeling those observations and measurements.  But, do those models tell me about the situation- and perspective-level normal contexts and potentials?  Do they tell me about the specifying and exemplar sign-interpretants?

If they do not, then is Shannon’s information theory biosemiotic?

02/3/25

Looking at Gustavo Caetano-Anolles’ Chapter (2024) “Evolution of Biomolecular Communication” (Part 9 of 10)

0382 Does Shannon’s information theory offer a metaphor for biosemiotics?

And, how weird and disturbing would that analogy be?

0383 Consider the hypothetical that exemplifies the author’s biphasic depiction of evolutionary growth.

Here is a picture.

0384 According to Shannon’s information theory, I should focus on the virtual nested form in the realm of actuality.

The perspective-level actuality2c of free glucose to the insect’s body2c virtually brings the situation-level actuality2b of the functionality of the claw and jaw combination achieved by bacteria in the insect’s gut2b into relation with the potential of the content-level actuality2a of glucose bound within the cellulose that the insect has eaten2a.

0385 My exterminator says that he recommends a new product.

Apparently, investigators at the Molecular Biology Department at the University of Slidell, in Louisiana, hatched a scheme for treating lumber with dilute concentrations of hydrofluoric acid.  They patented the process.

0386 Apparently, the fluoride replaces a hydroxy group on the beta-linked polysaccharides of wood, here and there.  The fluoride causes the claw part of the jaw and claw to not let go.  Apparently, one fluoride on one beta-linked polysaccharide can gum up the operations of a whole bacteria and the bacteria dies, which is no big deal, until the wood-eating insect’s gut digests the bacteria and frees that one fluoride-labeled beta-linked polysaccharide back into the gut, for another bacteria to pick up to digest.

In short, bacteria-killing fluoride-labeled beta-linked polysaccharides start to build up in the wood-eating insect’s gut and the insect gets less glucose, even as it continues to eat the treated wood.  This is no good.  So, the wood-eating insects move on.

Yes, the treated wood2a transmits a message into a channel within the wood-eating insect’s gut2b so the insect itself receives a signal to move on2c.

0387 What a sales pitch.  The explanation offers a specific mechanism for deterring wood-eating insects.  Plus, it fits a budget.

The economy of the exterminator’s proposal, along with the promised robustness of treatment and flexibility in application, convinced my neighbor to use the processed wood for his new shed, which replaces his old, well-infested, one.

I suspect that my neighbor secretly hopes that the wood-eating insects simply move over to my lot.  It is as if my neighbor2a transmits a message into a channel consisting of a trail of wood-eating insects to my untreated wood shed2bthat signals to me that I better build a new shed with treated lumber2c.